Table.
Demographic and Clinical Features of Study Population
| Patient No./Sex/Age, y | Tumor Location | Tumor Characteristics | Tumor Area, mm2 | Adjuvant Therapy | Recurrence After Primary Excision | Time to Recurrence | Treatment of Recurrence |
|---|---|---|---|---|---|---|---|
| 1/M/68 | Temporal bulbar, right eye | Separate focus of PAM; diffuse disease | 24 | Cryo plus MMC | Local recurrence | 3 y | MMC or IFN plus surgery |
| 2/F/65a | Plica and inferior palpebral, right eye; caruncle, right eye | Diffuse growth into tarsus/caruncle + large circumscribed palpebral lesion | 78 | Cryo plus IFN | Local recurrence | 10 mo | Exenteration |
| 3/F/52 | Temporal bulbar, right eye | Limbus, overlying cornea | 24.5 | Cryo | No | NA | NA |
| 4/F/51 | Nasal bulbar, left eye | Limbus, overlying cornea | 15 | Cryo plus MMC | Local recurrence | 3 mo | MMC or IFN plus surgery |
| 5/F/77 | Inferotemporal bulbar, left eye | Arising from PAM, diffuse along bulbar conjunctiva | 3 | Cryo | No | NA | NA |
Abbreviations: cryo, cryotherapy; IFN, interferon-alfa-2b; F, female; M, male; MMC, mitomycin C; NA, not applicable; PAM, primary acquired melanosis.
a
Patient died.