Table 2.
Genes with a significant difference in responder group mean gene expression following dosing
| Probe ID | Gene ID | Description | AR | SE | TS |
|---|---|---|---|---|---|
| A_23_P128333 | NM_002824 | Parathymosin (PTMS) | 0.0468 | 0.0095 | 4.94 |
| A_23_P76799 | NM_013448 | Bromodomain adjacent to zinc finger domain, 1 A (BAZ1A) | 0.1790 | 0.0401 | 4.47 |
| A_23_P104804 | NM_006006 | Zinc finger and BTB domain containing 16 (ZBTB16) | 0.2989 | 0.0719 | 4.16 |
| A_23_P13065 | AK001831 | Zinc finger, DHHC-type containing 13 (ZDHHC13) | 0.3003 | 0.0745 | 4.03 |
| A_23_P58321 | NM_001237 | Cyclin A2 (CCNA2) | 0.2885 | 0.0726 | 3.98 |
| A_23_P11507 | NM_015534 | Zinc finger, ZZ-type containing 3 (ZZZ3) | 0.2408 | 0.0608 | 3.96 |
| A_23_P128613 | NM_024089 | KDEL (Lys-Asp-Glu-Leu) containing 1 (KDELC1) | 0.5092 | 0.1286 | 3.96 |
| A_23_P120533 | NM_007219 | Ring finger protein 24 (RNF24) | −0.6434 | 0.1618 | −3.98 |
| A_23_P211180 | NM_000211 | Integrin, beta 2 (ITGB2) | −1.3192 | 0.3270 | −4.03 |
| A_23_P212180 | A_23_P212180 | Unknown | −0.0413 | 0.0070 | −5.93 |
| A_23_P259357 | BC040191 | Solute carrier family 35, member E4 (SLC35E4) | −0.0063 | 0.0010 | −6.21 |
| A_23_P75097 | NM_024895 | PDZ domain containing 7 (PDZD7) | −0.0181 | 0.0009 | −20.05 |
AR is the log base 2 difference in the mean of the gene expression response to acetaminophen in the dosing period from the mean gene expression in the acclimation period. SE is the standard error and TS is the test statistic from the discontinuous piecewise regression.