Table 4. Trends in age-standardized mortality rates associated with infectious disease (derived using joinpoint analysis), South Korea, 1983–2015*.

Disease	Mortality rate		AAPC, 1983–2015	Trend 1			Trend 2			Trend 3
	1983	2015		Period	APC		Period	APC		Period	APC
All infectious disease	43.5	44.6	0.44	1983–1991	−9.73		1991–2006	0.67		2006–2015	8.97
Respiratory tract infections	15.1	19.5	1.06	1983–1992	−8.89		1992–2007	1.83		2007–2015	11.47
Sepsis	0.8	4.0	3.80	1983–2000	8.62		2000–2003	−20.38		2003–2015	6.99
Tuberculosis	23.7	3.0	−5.97	1983–1989	−9.12		1989–2015	−5.55
Intestinal infections	4.3	0.9	−2.62	1983–1988	−14.30		1988–2004	−4.50		2004–2015	5.48
Vaccine-preventable diseases	1.1	0.0	−1.71	1983–1987	−10.97		1987–1996	−3.00		1996–2015	−0.33
CNS infections	3.1	0.3	−2.71	1983–1986	−13.94		1986–1992	−5.50		1992–2015	−1.62
Viral hepatitis	0.0	1.0	3.24	1983–1998	2.75		1998–2007	7.92		2007–2015	−4.99
HIV diseases	0.0	0.2	0.70	1983–1998	−0.01		1998–2001	2.85		2001–2015	0.77
Rheumatic heart diseases	0.5	0.2	−0.35	1983–1999	−1.40		1999–2002	9.31		2002–2015	−2.24

*AAPC, average annual percentage change; APC, annual percentage change in age-standardized mortality rate; CNS, central nervous system. Mortality rates expressed as deaths/100,000 population. Values in bold indicate where AAPC or APC differed significantly (p<0.05) from zero (by a 2-sided test for which the true AAPC was zero, calculated based on a t distribution; https://surveillance.cancer.gov/help/joinpoint/setting-parameters/method-and-parameters-tab/average-annual-percent-change-aapc).