Table. Epidemiologic, clinical, and laboratory testing features of 14 patients with Borrelia miyamotoi infections, northeastern China, May 2013–June 2015*.
| Characteristic |
Patient no. | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
14 |
|
| Epidemiologic features | ||||||||||||||
| Sex | F | M | F | M | M | M | M | M | M | F | M | M | M | M |
| Age, y | 46 | 30 | 31 | 47 | 41 | 43 | 49 | 52 | 10 | 65 | 36 | 48 | 52 | 43 |
| History of tick bite | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Place of exposure to ticks | Forest | Forest | Forest | Forest | Forest | Forest | Forest | Forest | Home | Forest | Forest | Forest | Forest | Forest |
| Tick bite location | Arm | Trunk | Neck | Ear | Leg | Trunk | Trunk | Trunk | Scalp | Arm | Trunk | Trunk | Trunk | Trunk |
| Days from tick
exposure to
illness onset |
18 |
28 |
16 |
5 |
3 |
7 |
7 |
25 |
4 |
10 |
26 |
6 |
4 |
40 |
| Clinical manifestations | ||||||||||||||
| Fever, °C | 38.4 | 39.7 | 39 | 39 | – | – | 39.6 | 38.5 | – | – | – | – | – | – |
| Asthenia | + | + | + | + | – | – | – | – | + | – | – | – | – | – |
| Headache | + | + | + | + | – | – | – | + | – | – | – | + | – | – |
| Anorexia | + | – | + | + | – | – | – | + | – | – | – | + | – | – |
| Myalgia | – | – | – | – | – | – | + | – | – | – | – | – | – | – |
| Arthralgia | – | + | + | – | – | – | + | – | – | – | – | – | – | – |
| Lymphadenopathy | – | – | – | – | – | – | – | – | + | – | – | – | – | – |
| Rash | – | – | – | – | – | – | – | – | – | + | – | – | – | – |
| Eschar |
– |
– |
– |
– |
– |
– |
– |
– |
+ |
– |
– |
– |
– |
– |
| Laboratory findings† | ||||||||||||||
| Leukocytes, 109/L | 7.9 | 9.6 | 8.9 | 11.7 | 5.1 | NA | 4.3 | NA | 9.9 | 7.6 | NA | 6.3 | 5.4 | 11.8 |
| Lymphocytes, 109 cells/L | 0.9 | 0.6 | 0.9 | 1.8 | 1.7 | NA | 0.3 | NA | 3 | 2.2 | NA | 2 | 2.5 | 1.2 |
| Neutrophils, 109 cells/L | 7.4 | 5.5 | 8.4 | 8.3 | 2.7 | NA | 3.9 | NA | 6 | 16.9 | NA | 4.2 | 2.7 | 9.7 |
| Platelets, 109/L | 164 | 130 | 173 | 210 | 218 | NA | 79 | NA | 298 | 200 | NA | 172 | 137 | 269 |
| AST, U/L | 94.4 | 30.5 | 13.9 | 31 | 16.7 | NA | 60 | NA | 11.4 | NA | NA | 22 | 10.7 | NA |
| ALT, U/L | 124.6 | 17.8 | 12.1 | 26.1 | 24.3 | NA | 71.6 | NA | 8 | NA | NA | 39.5 | 16.2 | NA |
| Hospital stay (d) | Yes (17) | Yes (3) | Yes (15) | Yes (20) | No | No | No | No | No | No | No | No | No | No |
| Co-infection | No | No | No | CRT | CRT | AC | No | No | No | No | No | No | No | No |
*AC, Anaplasma capra; ALT, alanine aminotransferase; AST: aspartate aminotransferase; CRT, Candidatus Rickettsia tarasevichiae; NA, not applicable; +, positive; –, negative. †Normal ranges: leukocyte count, 4–10 × 109 cells/L; lymphocyte count, 0.8–4 × 109 cells/L; neutrophil count, 2–7 × 109 cells/L; platelet count, 100–300 × 109/L; AST, 8–40 U/L; ALT, 5–40 U/L.