Table 2.
Univariate analysis of LBH expression and various clinicopathological parameters in 226 patients with HCC (log-rank test)
| Variable | All cases, n | Mean survival (months) | P-value |
|---|---|---|---|
| Age (years) | 0.52 | ||
| <51 | 107 | 80 | |
| ≥51 | 119 | 105 | |
| Gender | 0.348 | ||
| Male | 203 | 99.6 | |
| Female | 23 | 86.7 | |
| HbsAg | 0.744 | ||
| Positive | 207 | 100.3 | |
| Negative | 19 | 82.8 | |
| AFP (ng/mL) | 0.161 | ||
| <81 | 112 | 86.4 | |
| ≥81 | 112 | 92.7 | |
| Liver cirrhosis | 0.193 | ||
| No | 90 | 96.6 | |
| Yes | 127 | 85.8 | |
| Tumor size (cm) | 0.001* | ||
| <5.5 | 109 | 93.7 | |
| ≥5.5 | 115 | 87 | |
| AST/ALT | 0.002* | ||
| <1.4 | 115 | 92.4 | |
| ≥1.4 | 111 | 84.2 | |
| Relapse | 0.000* | ||
| No | 138 | 123.6 | |
| Yes | 66 | 67.2 | |
| Clinical stage | 0.004* | ||
| I–II | 179 | 108.4 | |
| III–IV | 47 | 62.7 | |
| LBH expression | 0.000* | ||
| Low | 206 | 111.4 | |
| High | 20 | 30.2 |
Note:
*
P<0.05.
Abbreviations: LBH, limb-bud and heart; HbsAg, hepatitis B surface antigen; HCC, hepatocellular carcinoma; AFP, alpha-fetoprotein; AST, aminotransferase; ALT, alanine aminotransferase.