Table 1.
Biomarker | Controls (n=30) | Patients (n=103) |
---|---|---|
TNFα (pg/mL) | 13.2±11.5 | 23.4±16.8NS |
HMGB1 (ng/mL) | 3.1±0.9 | 9.9±1.2p<001 |
PDMP (U/mL) | 8.2±1.5 | 27.9±4.6p<0.001 |
sVCAM-1 (ng/mL) | 627±219 | 1,866±1,182p<0.001 |
PAI-1 (ng/mL) | 9.3±2.5 | 36.8±7.9p<0.001 |
sEPCR (ng/mL) | 84±25 | 180±68p<0.001 |
Notes: Data are shown as mean ± SD. p-value, patients versus controls.
Abbreviations: TNFα, tumor necrosis factor α; HMGB1, high mobility group box protein 1; PDMP, platelet-derived microparticles; sVCAM-1, soluble vascular cell adhesion molecule-1; PAI-1, plasminogen activator inhibitor-1; sEPCR, soluble endothelial protein C receptor; NS, not significant.