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. 2018 Jan 19;13:467–477. doi: 10.2147/IJN.S151110

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© 2018 Li et al. This work is published and licensed by Dove Medical Press Limited

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Antibody responses in immunized BALB/c mice.

Notes: (A) Total IgG antibody against Toxoplasma gondii in the sera of BALB/c mice immunized with T. gondii Exo-R or Exo-M, PBS and Blank control on weeks 0, 2, 4, 6 after the first inoculation. (B) IgG1, and (C) IgG2a against T. gondii in the sera of the immunized BALB/c mice 2 weeks after the last inoculation. Results are expressed as the mean OD 450± SD and are representative of three individual experiments. n=14 animals per group, *p<0.05 or **p<0.01 compared with PBS or Blank control.

Abbreviations: Exo-R, exosomes from RH strain; Exo-M, exosomes from ME 49 strain; PBS, phosphate buffered saline.