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. 2018 Jan 24;13(1):e0190300. doi: 10.1371/journal.pone.0190300

Fig 1. Effect of Ac-SDKP on cardiac rupture incidence, mortality rate, and infarct size in myocardial infarction.

Fig 1

Out of 95 mice analyzed at 7 days post-MI, 38 died from cardiac rupture, and 5 died from other causes. In myocardial infarction, Ac-SDKP decreased A) incidence of cardiac rupture from 51.0% (vehicle treated) to 27.3% (Ac-SDKP treated) and B) mortality from 56.9% (vehicle treated) to 31.8% (Ac-SDKP treated). C) In a new group of 25 animals, Ac-SDKP tends to decrease infarct size, but it does not reach statistical significance (p = 0.13; power < 0.70).