Table 3. Relationships between five year change in adipose volumes with change in thoracic and lumbar volumetric bone mineral density.

	Β Coefficent (Standard Error); P value
Adipose Volume	Thoracic vBMD Change	Lumbar vBMD Change
Inter-muscular (minimally adjusted)
Change	0.473 (0.201); 0.019	0.231 (0.155); 0.14
Inter-muscular (fully adjusted)
Change	0.432 (0.198); 0.029	0.235 (0.160); 0.14
Subcutaneous (minimally adjusted)
Change	0.035 (0.013); 0.006	0.037 (0.010); 0.0003
Subcutaneous (fully adjusted)
Change	0.040 (0.013); 0.002	0.045 (0.011); <0.0001
Visceral (minimally adjusted)
Change	0.055 (0.023); 0.016	0.019 (0.018); 0.28
Visceral (fully adjusted)
Change	0.055 (0.023); 0.016	0.018 (0.019); 0.34
Pericardial (minimally adjusted)
Change	0.101 (0.066); 0.13	0.022 (0.052); 0.67
Pericardial (fully-adjusted)
Change	0.080 (0.066); 0.22	0.027 (0.057); 0.64

Minimally adjusted model: baseline thoracic/lumbar vBMD and study interval;

Fully adjusted model: baseline thoracic/lumbar vBMD, study interval, age, sex, smoking, hypertension, body mass index, HbA1c, estimated glomerular filtration rate, steroid use, hormonal replacement therapy (women), calcium supplements, and vitamin D supplements (inter-muscular adipose volume and inter-muscular adipose volume change are included only in the lumbar vBMD subcutaneous change model).

Abbreviations: vBMD, volumetric bone mineral density.