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. 2018 Jan 24;13(1):e0191636. doi: 10.1371/journal.pone.0191636

Table 1. Characteristics of the 11 studies included in a systematic review and diagnostic accuracy meta-analysis.

Study ID Study setting Study location Study scene Mean age (years) Sample size (n) Patients’ characteristics US views US operators’ experience The time US was performed
Aichinger 2012 Unknown Austria Pre-hospital 70.3 11 Non-traumatic Subxiphoid A 2-h course in echocardiography During a rhythm and pulse check
Blaivas 2001 Single USA In-hospital 71 38 Non-traumatic Subxiphoid; if unable to obtain, use parasternal views Ultrasound trained and credentialed The duration of the pulse check
Breitkreutz 2010 Single Germany Pre-hospital 65±15 51 Both One of three views Having undergone the standard FEER training program During an ALS-conformed interruption of CPR
Flato 2015 Single Brazil In-hospital 59.75±18.11 32 Both Various views Had a 60-min lecture on ALS-conformed-TTE During the intervals for rhythm check for 10s
Chardoli 2012 Multicenter Iran In-hospital 58±6.1 50 Both Subxiphoid Attended a teaching course to performing echocardiography Just in the first NFI
Salen 2001 Multicenter USA In-hospital Unknown 55 Non-traumatic Subxiphoid view; the apical view as an adjunct in obese patients Received a 4-h trauma sonography course During the pulse check pause of the ALS
Salen 2005 Multicenter USA Pre-hospital/in-hospital 16–94 34 Non-traumatic Subxiphoid or parasternal Physician sonographers Examinations during the pulse check
Tayal 2003 Single USA In-hospital 57±15 20 Non-traumatic Various views Trained with a 20-h ultrasound course During CPR
Gaspari 2016 Multicenter USA and Canada In-hospital 64.2±17.4 414 Non-traumatic Subxyphoid or parasternal long axis views Emergency physician’s credentialed in bedside ultrasound by their individual hospitals During pauses in resuscitation
Kim 2016 Single Korea Pre-hospital 63.9±14.5 8 Non-traumatic Subcostal or parasternal window The senior emergency resident or emergency specialist who had≥3 years’experience in emergency echocardiography During pulse checks
Tomruk 2012 Single Turkey In-hospital 61.6±17.9 64 Both Subxiphoid cardiac approach Theoretical and hands-on training in cardiac ultrasonography During the initial assessment

PEA, pulseless electrical activity; ROSC, restoration of spontaneous circulation which was defined as a return of spontaneous circulation for ≥20 mins or ROSC upon hospital admission; US, ultrasound; ALS, advanced life support; NFI, no flow interval; TTE, transthoracic echocardiography; in-hospital indicates that bedside ultrasound was not used until arrival at hospital; pre-hospital indicates that ultrasound was used at the scene; Unknown, the data was unable to be obtained; FEER, focused echocardiographic evaluation in resuscitation; CPR, cardiopulmonary resuscitation.