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. 2018 Jan 11;12(1):e0006184. doi: 10.1371/journal.pntd.0006184

Fig 3. M. perstans microfilaremic individuals present elevated filarial-specific IgG4 in sera.

Fig 3

Sera from and M. perstans microfilaremic (Mp MF+, n = 11) and amicrofilaremic (Mp MF-; n = 6) individuals were analyzed for total and M. perstans-specific immunoglobulin levels. (A) total IgE (μg/ml) (B) total IgG4 (μg/ml), (C) ratio of total IgE/IgG4, (D) M. perstans-specific IgE (OD), (E) M. perstans-specific IgG4 (OD) and (F) ratio of M. perstans-specific IgG4/IgE. Graphs show box whiskers with median, interquartile ranges and outliers. Statistical significances between the indicated groups were obtained using the Mann-Whitney-U-test.