Table 6.
Univariate and multivariate predictors of changes in left ventricular ejection fraction over time (12 month follow-up)
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Coefficient (95% CI) | p value | Coefficient (95% CI) | p value | |
| Clinical variables | ||||
| Age | -0.043 (-0.259 to 0.173) | 0.699 | ||
| Sex | 0.179 (-2.89 to 3.252) | 0.909 | ||
| Hypertension | -3.673 (-6.938 to -0.408) | 0.318 | -0.667 (-3.548 to 2.214) | 0.650 |
| Diabetes mellitus | -1.753 (-5.187 to 1.681) | 0.318 | ||
| eGFR < 60 mL/min | 1.475 (-2.253 to 5.203) | 0.439 | ||
| Paroxysmal/chronic atrial fibrillation | 1.937 (-2.828 to 6.702) | 0.426 | ||
| Coronary artery disease | 0.274 (-2.801 to 3.349) | 0.861 | ||
| Echocardiography | -0.511 (-0.619 to -0.403) | |||
| LVEF | -0.466 (-0.554 to -0.378) | <0.001 | 0.033 (-0.061 to 0.127) | <0.001 |
| Mean gradient (≥ 50.05 mm Hg) | -0.143 (-0.24 to -0.043) | 0.006 | 0.491 | |
| Aortic valve area | -0.216 (-8.227 to 7.795) | 0.958 | -0.131 (-0.286 to 0.024) | |
| LV diastolic diameter | 0.166 (-0.001 to 0.333) | 0.053 | 0.098 | |
| Variables of the procedure | ||||
| Moderate or greater AR | -0.085 (-4.595 to 4.425) | 0.971 | -4.917 (-8.141 to -1.693) | |
| Within 30 days from PPI | -5.55 (-9.221 to -1.879) | 0.003 | 0.003 | |
| CoreValve | -0.708 (-4.577 to 3.161) | 0.720 | ||
| Pre-dilation | -2.516 (-5.648 to 0.616) | 0.117 | 1.652 (-1.772 to 5.076) | |
| HF (III or IV) | 5.578 (1.676 to 9.480) | 0.005 | 0.345 | |
AR: aortic regurgitation; CI: confidence interval; eGFR: estimated glomerular filtration rate; LVEF: left ventricular ejection fraction; LV: left ventricular; PPI: permanent pacemaker implantation; HF: heart failure. Linear regression; multivariate model R2 = 0.347.