Figure 6.

Effects of AR-42 on JNK signaling pathways in chronic pancreatitis. (A) Representative western blot images and (B) quantification of protein expression levels of JNK1/2 in the spinal dorsal horn. (C) Quantification of immunostaining density of MOR following AR-42 treatment. Data are presented as the mean ± standard error. *P<0.05 vs. control; ^#P<0.05 vs. group untreated with AR-42 at the same time point. MOR, µ-pioid receptor; JNK, c-Jun N-terminal kinase; TNBS, trinitrobenzene sulfonic acid; w, weeks; HDAC, histone deacetylase; i, inhibitor.