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(A) Dose-response curves for LoRR in rats. A fit of the dose-response relationships yielded ED50 values of 0.77 ± 0.17 mg/kg for etomidate and 72 ± 13 mg/kg for dimethoxy-etomidate. (B) Dose-response curves for LoRR duration in rats. In both panels, each symbol is the result obtained from a single rat experiment.
