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. 2017 Oct 10;38(6):3327–3334. doi: 10.3892/or.2017.6019

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Copyright: © Meng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — BAF53a associates with EMT in glioma. The expression correlation of BAF53a, vimentin and E-cadherin in glioma cells detected by real-time PCR (A) and western blotting (B), results showed that vimentin expression was upregulated along with BAF53a overexpression, but E-cadherin expression was decreased; when BAF53a was knocked down, they had inverse expression. (C) The phase contrast images of BAF53a-interfered U87 cells, results showed cells became mesenchymal-like in BAF53a overexpression, and cells changed to oval or cobblestone-like appearance in BAF53a knockdown. (D) The representative images of expression correlation of BAF53a, vimentin and E-cadherin in glioma tissues detected by IHC. (E) The Spearman's rank correlation test indicated that BAF53a and vimentin expression were positively correlated, while BAF53a and E-cadherin expression were negatively correlated.