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. 2017 Nov 14;39(1):151–159. doi: 10.3892/or.2017.6097

Figure 5.

Figure 5.

Correlation of the number of CD8+ T cells before and after NAC with the HMGB1 and calreticulin score, and patient survival in breast cancer patients. (A) Evaluation of the number of CD8+ T cells before and after NAC. Representative IHC of CD8 is shown. (B) Evaluation of the number of CD8+ T cells before and after NAC in pathological response. (C) Correlation of the HMGB1/calreticulin score with the number of CD8+ T cells before and after NAC. (D) Correlation of the degree of infiltrating CD8+ T cells before and after NAC with clinical outcomes. *p<0.05. HMGB1, high-mobility group box 1 protein; NAC, neoadjuvant chemotherapy. n.s. not significant.