Figure 11.

Positive staining of the P2Y2 receptor in normal tumor-adjacent breast and breast cancer tissues. In normal tumor-adjacent breast tissues, nuclear staining of the P2Y2 receptor was observed in various ductal myoepithelial cells (A, magnification, ×200). In the breast tumor tissues, relative overexpression of the P2Y2 receptor was noted at the invasive edge of the tumor (B, magnification, ×200), in infiltrating tumor cells in the breast adipose tissue (C, magnification, ×200) or the cancer embolus in the lymphatic sinuses (D, magnification, ×200) compared to the tumor core. Scale bars, 50 µm.