Table I.
Statistical analysis of the expression of the P2Y2 receptor (mean ± SD) and clinicopathological characteristics of the breast cancer cases.
| Characteristics | N | P2Y2 | P-value |
|---|---|---|---|
| Grade | 0.023a | ||
| 1 | 36 | 6.49±2.58 | |
| 2 | 122 | 6.26±2.05 | |
| 3 | 38 | 4.77±1.70 | |
| TNM stage | 0.511b | ||
| I+II | 134 | 6.11±2.24 | |
| III+IV | 63 | 5.80±2.92 | |
| Lymph node metastasis | 0.407b | ||
| Yes | 116 | 6.17±2.03 | |
| No | 81 | 5.79±2.29 | |
| Distant metastasis | 0.360b | ||
| Yes | 28 | 6.53±2.70 | |
| No | 170 | 5.93±2.20 | |
| Location in the tumor | 0.020b | ||
| Tumor core | 92 | 1.99±1.18 | |
| Invasive edge or cancer embolus | 92 | 2.48±1.63 | |
| NPI | 0.141a | ||
| Good | 28 | 6.30±2.42 | |
| Moderate | 115 | 6.28±2.18 | |
| Poor | 52 | 5.28±2.82 | |
| ER expression | 0.755b | ||
| Yes | 83 | 5.94±1.27 | |
| No | 104 | 6.09±2.08 | |
| HER2 amplification | 0.008a | ||
| Yes | 76 | 5.27±2.03 | |
| No | 114 | 6.47±3.08 |
a
Means for one-way ANOVA
b
means for independent-samples t-test. TNM, tumor-node-metastasis, ER, estrogen receptor; NPI, Nottingham Prognostic Index.