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. 2017 Nov 16;39(1):160–172. doi: 10.3892/or.2017.6100

Figure 8.

Figure 8.

Effects of cisplatin resistance on RB cell growth, viability, proliferation and apoptosis. (A-C) Growth curves, (D) WST-1 assays, (E) BrdU counts and (F) DAPI cell counts of cisplatin-resistant (CisPt) Y-79 (A), WERI-Rb1 (B) and RBL-355 cells (C) vs. control cells (Ctr) revealed that cisplatin resistance led to a significant decrease in growth kinetics (A-C), cell viability (D) and proliferation (E). Cisplatin treatment, however, still significantly increased apoptosis levels in all cisplatin-resistant cell lines (F). Values are means of at least 3 independent experiments ± SEM; *P<0.05, **P<0.01, ***P<0.001 compared to the control group calculated by Student's t-test.