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. 2017 Dec 11;39(2):537–544. doi: 10.3892/or.2017.6149

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Copyright: © Ochiai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Cell cycle distribution analysis of the U-87MG and U-138MG cells which underwent treatment with ribavirin (untreated cells serving as the control) for 8 or 48 h. The histogram depicting the FACS data demonstrates an increase in the population of cells in the G₀/G₁ phase following ribavirin treatment, with a time-lapse, indicating that the antitumor efficacy of ribavirin resulted from the accumulation of cells in the G₀/G₁ phase. The results are expressed as the mean ± SE. **P<0.01 (Student's t-test).