Table 3.

Adjusted mean [95% confidence interval (CI)] proportion of cycles resulting in implantation, live birth, and clinical pregnancy by quartile of urinary organophosphate flame retardant metabolite concentrations among 211 women undergoing 297 in vitro fertilization (IVF) cycles.

Condition	$\mathrm{\Sigma }\text{PFR}$	BDCIPP	DPHP	ip-PPP
Implantation
Q1	0.71 (0.59, 0.81)	0.72 (0.59, 0.81)	0.69 (0.56, 0.79)	0.74 (0.62, 0.83)
Q2	0.62 (0.49, 0.73)	0.58 (0.46, 0.70)	0.64 (0.52, 0.75)	0.50 (0.37, 0.62)
Q3	0.57 (0.45, 0.69)	0.53 (0.41, 0.65)	0.56 (0.44, 0.68)	0.61 (0.48, 0.72)
Q4	0.49 (0.37, 0.62)*	0.56 (0.43, 0.67)	0.50 (0.38, 0.62)*	0.54 (0.41, 0.66)*
p-trend	0.02	0.06	0.02	0.05
Pregnancy
Q1	0.63 (0.50, 0.74)	0.61 (0.49, 0.73)	0.61 (0.49, 0.72)	0.63 (0.51, 0.74)
Q2	0.54 (0.42, 0.66)	0.50 (0.38, 0.62)	0.55 (0.42, 0.66)	0.40 (0.29, 0.53)
Q3	0.50 (0.38, 0.62)	0.47 (0.35, 0.59)	0.48 (0.36, 0.60)	0.51 (0.39, 0.63)
Q4	0.37 (0.26, 0.50)*	0.45 (0.33, 0.57)	0.39 (0.28, 0.52)*	0.48 (0.36, 0.61)
p-trend	0.004	0.06	0.01	0.19
Live birth
Q1	0.48 (0.35, 0.61)	0.49 (0.36, 0.61)	0.47 (0.34, 0.59)	0.53 (0.40, 0.65)
Q2	0.42 (0.30, 0.55)	0.36 (0.24, 0.48)	0.42 (0.30, 0.55)	0.35 (0.24, 0.47)
Q3	0.38 (0.27, 0.51)	0.36 (0.25, 0.49)	0.37 (0.26, 0.50)	0.35 (0.24, 0.48)
Q4	0.30 (0.20, 0.43)*	0.36 (0.25, 0.49)	0.31 (0.21, 0.44)	0.35 (0.24, 0.48)
p-trend	0.05	0.20	0.07	0.05

Note: Adjusted models control for maternal age (continuous), body mass index (continuous), race/ethnicity (black/Asian/other, white/Caucasian), year of IVF treatment cycle (continuous), and primary Society for Assisted Reproductive Technology (SART) infertility diagnosis at study entry (female, male, unknown). Adjusted means are presented for the mean maternal age (35.2), body mass index (23.9), race/ethnicity (white), year of IVF treatment cycle (2010), and primary SART infertility diagnosis at study entry ($\text{female}=1$ $\text{male}=0$, $\text{unexplained}=0$). BDCIPP, bis(1,3-dichloro-2-propyl) phosphate; DPHP, diphenyl phosphate; ip-PPP, isopropylphenyl phenyl phosphate; PFR, organophosphate flame retardant.

^*Significantly different from Q1 at the $p=0.05$ level.