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. 2017 Aug 4;125(8):087004. doi: 10.1289/EHP1014

Table 3.

Comparison of EC20 values of the components of mixture III with the concentrations present in a mixture causing 50% suppression of testosterone.

Chemical EC20 (M) Individual dose in mix III at 105M
BPA 1.30×106 5.34×107
Clomifene 6.21×107 2.55×107
Ketoconazole 5.98×107 2.46×107
Valproic acid 5.03×107 2.07×107
BPS 8.64×106 3.55×106
Chlordecone 5.92×106 2.43×106
Imazalil 6.70×106 2.76×106
Theophylline 3.67×108 1.69×108
Mixture III effect   53% reduction in the testosterone production

Note: EC20 is the concentration (M, mol/L) of each substance associated with a 20% reduction of testosterone production. Mix, mixture.