Table 5.

Odds ratios and 95% confidence intervals for associations between quartiles of prenatal brominated flame retardant serum concentrations and ID (relative to GP controls).

BFR/quartile	ID ($n$)	Control ($n$)	Model 1a	Model 2b	p-Trendc
BB153
Q1	41	93	1.0	1.0	0.62
Q2	52	92	1.21 (0.72, 2.05)	1.46 (0.84, 2.54)
Q3	30	100	0.71 (0.40, 1.26)	0.95 (0.51, 1.79)
Q4	37	98	0.84 (0.48, 1.45)	1.34 (0.72, 2.51)
BDE-28
Q1	38	94	1.0	1.0	0.95
Q2	47	93	1.24 (0.72, 2.13)	1.30 (0.73, 2.31)
Q3	34	90	0.97 (0.55, 1.73)	1.00 (0.54, 1.82)
Q4	36	99	1.06 (0.60, 1.86)	1.12 (0.62, 2.04)
BDE-47
Q1	46	103	1.0	1.0	0.30
Q2	52	105	1.09 (0.66, 1.81)	1.04 (0.62, 1.77)
Q3	48	104	1.06 (0.63, 1.77)	0.93 (0.54, 1.58)
Q4	35	104	0.81 (0.47, 1.38)	0.76 (0.43, 1.34)
BDE-99
Q1	46	107	1.0	1.0	0.14
Q2	46	100	0.93 (0.56, 1.55)	0.87 (0.51, 1.49)
Q3	48	102	1.06 (0.64, 1.78)	0.85 (0.50, 1.46)
Q4	36	98	0.75 (0.44, 1.29)	0.64 (0.36, 1.13)
BDE-100
Q1	46	99	1.0	1.0	0.55
Q2	45	102	0.89 (0.53, 1.50)	0.86 (0.50, 1.48)
Q3	50	103	1.07 (0.65, 1.79)	1.02 (0.60, 1.73)
Q4	35	103	0.77 (0.45, 1.32)	0.78 (0.44, 1.37)
PBDE153
Q1	53	95	1.0	1.0	0.56
Q2	48	103	0.93 (0.56, 1.53)	1.01 (0.60, 1.70)
Q3	41	107	0.74 (0.44, 1.24)	0.83 (0.49, 1.42)
Q4	34	102	0.71 (0.41, 1.20)	0.90 (0.51, 1.62)
Sumd
Q1	45	94	1.0	1.0	0.14
Q2	42	94	0.84 (0.52, 1.37)	0.87 (0.52, 1.43)
Q3	44	94	0.91 (0.56, 1.47)	0.87 (0.53, 1.43)
Q4	24	94	0.53 (0.31, 0.92)	0.58 (0.33, 1.03)

Note: GP, general population controls; ID, intellectual disability/developmental delay without autism.

^aModel 1: logistic regression adjusted for study matching factors (child sex, month and year of birth).

^bModel 2: $\text{Model}1+\text{maternal}\text{age}$ (continuous), maternal race/ethnicity (non-Hispanic white, Asian, Black/Pacific Islander/or other, Hispanic, or Missing), maternal weight at time of sample collection (quartiles), parity (multi- vs. primiparous), and maternal education ($<\text{high}\text{school}$, high school, college, graduate, missing).

^cp-Trend from the median value variable, adjusted as Model 2.

^dSum of all congeners shown in this table (those with at least 55% of study population with values $>\text{LOD}$).