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. Author manuscript; available in PMC: 2018 Nov 8.
Published in final edited form as: Cell Host Microbe. 2017 Oct 26;22(5):601–614.e5. doi: 10.1016/j.chom.2017.09.009

Figure 3. DC8 CIDRα1.1 and group A CIDRα1.7 EPCR-binding transcripts are enriched in CM cases with severe swelling and fatal outcomes.

Figure 3

(A) Schematic diagrams of EPCR-binding head structures by CIDRα1 sub-classification and the domain arrangement for dual EPCR and ICAM-1-binding (CIDRα1-DBLβ1/3) sequences.

(B) Heat map of median values of CIDRα1 subtype and ICAM-1-binding motif expression (dual EPCR and ICAM-1 binders).

(C) Bar graphs showing transcript levels of CIDRα1 subtypes and ICAM-1-binding motif. Median and IQR are indicated.

(D) Spearman correlations of transcript levels for individual EPCR-binding CIDRα1 subtypes and ICAM-1-binding motif amongst CM cases. Rho and statistical significance (correcting for multiple comparisons) are indicated.

See also Figure S2 and Tables S3–5.