Table 1.
Baseline Characteristics According to 6-Year Category of Change in hs-cTnT Among Persons With Detectable Baseline Troponin (hs-cTnT ≥5ng/L) and Without Cardiovascular Disease at ARIC Visit 2 (1990–1992)
| Covariates | hs-cTnT (ng/L) <5 (n=599) |
hs-cTnT (ng/L) ≥5 (n=2,418) |
p-value |
|---|---|---|---|
| Age (years) | 56.5 (5.6) | 58.9 (5.6) | <0.001 |
| Male | 226 (38%) | 1,635 (68%) | <0.001 |
| Black | 142 (24%) | 609 (25%) | 0.45 |
| Education (high school graduate) | 486 (81%) | 1,884 (78%) | 0.07 |
| Total Cholesterol(mg/dL) | 213.1 (40.6) | 207.7 (39.5) | 0.32 |
| Systolic BP (mmHg) | 119.5 (17.4) | 125.2 (19.0) | 0.02 |
| Diastolic BP (mmHg) | 71.7 (10.3) | 73.5 (10.5) | 0.09 |
| Antihypertensive Use | 165 (28%) | 861 (36%) | <0.001 |
| Diabetes Mellitus | 58 (10%) | 456 (19%) | <0.001 |
| eGFR (<60 mL/min/1.73m3) | 7 (1.2%) | 61 (2.5%) | 0.05 |
| Left ventricular hypertrophy | 11 (1.8%) | 81 (3.4%) | 0.05 |
| Alcohol consumption* | 0.36 | ||
| Current Excessive | 30 (5%) | 169 (7%) | |
| Current Moderate | 308 (51%) | 1,203 (50%) | |
| Former | 124 (21%) | 508 (21%) | |
| Never | 137 (23%) | 538 (22%) | |
| Average Life’s Simple 7 Score | 7.9 (2.1) | 7.3 (2.2) | <0.001 |
| Healthy Diet Score | 0.34 | ||
| Score 4-5 | 39 (6.5%) | 152 (6.3%) | |
| Score 2-3 | 426 (71%) | 1,655 (68%) | |
| Score 0-1 | 134 (22%) | 611 (25%) | |
| Body Mass Index (kg/m2) | <0.001 | ||
| BMI 18-24.9 | 199 (33%) | 594 (25%) | |
| BMI 25-29.9 | 250 (42%) | 1,009 (42%) | |
| BMI ≥30 | 150 (25%) | 815 (34%) | |
| Physical Activity† | 0.40 | ||
| Ideal | 133 (22%) | 477 (20%) | |
| Intermediate | 148 (25%) | 625 (26%) | |
| Poor | 318 (53%) | 1,316 (54%) | |
| Smoker‡ | 0.001 | ||
| Ideal | 290 (48%) | 1,000 (41%) | |
| Intermediate | 213 (36%) | 1,064 (44%) | |
| Poor | 96 (16%) | 354 (15%) | |
| Blood Pressure (mmHg) | <0.001 | ||
| SBP<120 and DBP<80 | 319 (53%) | 1,006 (42%) | |
| SBP 120-139 or DBP 80-89 | 197 (33%) | 888 (37%) | |
| SBP≥ 140 or DBP ≥90 | 83 (14%) | 524 (22%) | |
| Fasting Glucose (mg/dL) | <0.001 | ||
| <100 | 263 (44%) | 849 (36%) | |
| 100-125 | 282 (47%) | 1,166 (48%) | |
| ≥126 | 54 (9%) | 403 (17%) | |
| Total Cholesterol (mg/dL) | 0.008 | ||
| <200 | 233 (39%) | 1,105 (46%) | |
| 200-239 | 237 (40%) | 877 (36%) | |
| ≥240 | 129 (22%) | 436 (18%) |
Excessive Alcohol Consumption: >14 drinks/week in men, >7 drinks/week in women; Moderate Alcohol Consumption: 1–14 drinks/week in men, 1–7 drinks/week in women
Ideal Physical Activity: ≥75 mins/week or Moderate Activity ≥ 150 mins/week; Intermediate Physical Activity: Vigorous Activity 1-74 mins/week or Moderate Activity 1-149 mins/week; Poor Physical Activity: 0 mins/week any activity
Ideal Smoking Category: Never smoker or quit >12 months ago; Intermediate Smoking Category: Former smoker, quit ≥12 months ago; Poor Smoking Category: Current Smoker