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. 2017 Dec 26;22(2):768–777. doi: 10.1111/jcmm.13441
• Introduction
• Current understanding of the mechanisms underlying ICH‐induced brain injury
• Phagocytosis in haematoma resolution
• Potential endogenous haematoma scavenger receptors after ICH
• CD36
• CD47
• SRA
• Hp‐Hb‐CD163
• Hx‐Heme‐LRP1
• The upstream regulatory mechanism and intervention strategy for scavenger receptors after ICH
Nuclear factor erythroid 2‐related factor 2 (Nrf2)
Peroxisome proliferator‐activated receptor‐γ (PPAR‐γ)
• Potential treatment options/strategies for haematoma resolution via CD36
PPAR‐γ agonists
Nrf2 agonists
• The agonists for the other scavenger receptors
CD163 agonists
Haptoglobin(Hp) and haemopexin(Hx) agonists
LRP1 agonists
SRA agonists
CD47 agonists
Iron chelators
Conclusion
Acknowledgements
Conflict of interest