• Introduction |
• Current understanding of the mechanisms underlying ICH‐induced brain injury |
• Phagocytosis in haematoma resolution |
• Potential endogenous haematoma scavenger receptors after ICH |
• CD36 |
• CD47 |
• SRA |
• Hp‐Hb‐CD163 |
• Hx‐Heme‐LRP1 |
• The upstream regulatory mechanism and intervention strategy for scavenger receptors after ICH |
‐ Nuclear factor erythroid 2‐related factor 2 (Nrf2) |
‐ Peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) |
• Potential treatment options/strategies for haematoma resolution via CD36 |
‐ PPAR‐γ agonists |
‐ Nrf2 agonists |
• The agonists for the other scavenger receptors |
‐ CD163 agonists |
‐ Haptoglobin(Hp) and haemopexin(Hx) agonists |
‐ LRP1 agonists |
‐ SRA agonists |
‐ CD47 agonists |
‐ Iron chelators |
• Conclusion |
• Acknowledgements |
• Conflict of interest |