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. 2017 Nov 29;22(2):1257–1271. doi: 10.1111/jcmm.13404

Figure 6.

Figure 6

Ectopic expression of ADAMTS9 inhibits invasion of BT549 and SK‐BR‐3 cells, and suppresses angiogenesis in vitro. (A) Cell motility of vector‐ and ADAMTS9‐transfected cells (BT549 and SK‐BR‐3) were tested by transwell cell invasion assays. Results from three independent experiments were quantified as mean ± S.D. (B) Conditioned media from vector‐ and ADAMTS9‐transfected BT549 cells suppressed HUVEC tube formation. (C) mRNA expression levels of VEGFA were examined by qRT‐PCR in vector‐ and ADAMTS9‐transfected cells (BT549 and SK‐BR‐3). (D) Protein expression levels of VEGFA and p‐VEGFR2 in vector‐ and ADAMTS9‐transfected cells (BT549 and SK‐BR‐3). **P < 0.01, ***P < 0.001.