Table 1.

Clinical disease characteristics of patients

Patients	Gender	Age	BCR/ABL transcript levels	HGB (g/dl)	WBC (103/μl)	PLT (103/μl)	LDH (mg/dl)	Liver (cm)	Spleen (cm)	Blast count	Sokal score	HASFORD score	M‐MDSC (%)	Gr‐MDSCs (%)
1	M	67	81.37	11.2	72.2	355	2087	0	0	0	Low	Int	5.3	86.9
2	M	77	105.84	14.2	54.6	391	1426	0	0	0	Intermediate	Low	31	85
3	F	73	59.77	11.1	30.7	651	–	0	0	0	Low	–	0.7	72.7
4	M	56	66.29	12	164	526	2418	2	0	0	High	Intermediate	20.02	82
5	F	69	58.002	12.1	34	607	–	0	0	0	Intermediate	Low	10.2	81.4
6	M	84	45.1	14	50.3	285	873	0	0	0	Intermediate	Intermediate	23	79
7	M	51	41.59	12.5	38.4	368	–	0	0	0	Low	Low	26.9	87
8	F	56	20.41	12.6	95	463	668	0	–	0	Intermediate	–	29.8	79.4
9	M	62	79.85	11.3	331	96	–	6	4	5	High	Intermediate	37.7	85.4
10	M	59	39.74	12.4	152.24	527	–	2	3,5	0	Intermediate	–	50	88.7
11	M	59	25.14	15.3	22.8	20	–	0	0	0	Low	Intermediate	18.9	87
12	F	48	81.88	8.1	288	458	1043	2	14	3	High	Intermediate	41	86
13	F	71	48.16	9.2	70.5	338	2230	–	–	–	Intermediate	Intermediate	46.8	89
14	M	70	349.51	13.5	71.2	370	715	0	0	1	Intermediate	Intermediate	81.2	79
15	F	66	126.73	12.9	68.4	294	888	2	3	0	Intermediate	Intermediate	12.4	82
16	M	38	65.61	13.6	28.4	232	–	0	0	0	Low	Low	28.5	83.4
17	M	54	74.22	12.7	58	201	–	–	–	–	Low	Low	14.7	82
18	M	21	126.51	14.2	144	107	1247	0	6	1	Low	Low	81.6	83.7
19	M	53	142.78	16.6	34	311	288	0	3	0	Low	Intermediate	63	83
20	M	61	33.66	14.4	51.6	399	983	0	0	1	Low	Low	25	81
21	M	48	40.33	9.9	256	350	1074	7	14	1	Intermediate	Low	41	90
22	F	64	28.21	10.6	128.4	531	1147	0	2	1	Intermediate	Intermediate	1	58.3
23	F	57	122.97	11.4	156.6	273	1124	2	1	1	Low	Intermediate	61	88
24	M	36	56.24	10.8	55	208	1352	7	8	1	Low	Low	42.4	87
25	M	52	14.89	10.2	46	418	1820	0	2	1	Low	Intermediate	25	78
26	F	58	150.04	10.7	122.5	361	1683	0	3	1	Intermediate	Intermediate	50	75
27	F	65	191.66	15.3	87	252	688	0	0	0	Low	Low	91.2	50
28	F	72	71.98	13	111	168	345	4	2	2	Intermediate	Intermediate	14.4	75
29	F	78	48.26	11.7	77	651	–	0	1	2	High	Intermediate	5.4	64
30	M	37	153.59	12.8	91.6	344	1635	0	0	0	Low	Low	2.8	82.5
31	M	60	47	11	70	368	873	0	0	0	Intermediate	Intermediate	28	88
32	M	53	23.8	13	44	343	1820	0	2	1	Low	Intermediate	25	79
33	F	62	31.5	11	22	98	–	0	0	0	Low	Low	25.8	72
34	F	73	68.8	14	315	543	723	6	4	5	High	Intermediate	55	75
35	F	67	58.7	12.6	120	521	–	2	2	0	Intermediate	–	50	83
36	M	58	23.00	12.4	23	44	–	0	0	0	Low	Intermediate	16	87
37	M	47	78.2	11.9	98	98	1043	2	0	3	High	Intermediate	46	86
38	M	47	63	13.3	195	345	668	0	2	0	Intermediate	–	44	86
39	M	55	21	12.1	54	430	–	0	0	0	Intermediate	Low	11	78
40	F	63	120	10.7	70	370	1683	2	3	1	Intermediate	Intermediate	50	81
41	M	43	44.6	12	122	333	2230	–	–	–	Intermediate	Intermediate	37	77
42	M	69	328	9	71	370	715	0	0	1	Intermediate	Intermediate	83.2	84

The frequency and the functional characteristics of MDSC analysed in the PB from patients with CML at diagnosis. HD were age‐matched. (F, female; M, male; HGB, haemoglobin; WBC, white blood cells; PLT, platelets; LDH, lactate dehydrogenase. BCR/ABL transcipt levels are calculated as BCR‐ABL/ABL).