Figure 1.

Leptin action during the first stages of pregnancy. Leptin seems to play a crucial role during the first stages of pregnancy as it modulates critical processes such as implantation and placentation, as well as foetus development. The figure summarizes the most important actions of leptin during early gestation (green), highlighting its role in the maternal–foetal interface. It is also shown the different type of cell which expresses leptin receptor (LEPR) and produce leptin (violet). CT: cytotrophoblast, ST: syncytiotrophoblasts.