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. 2018 Jan 24;9:359. doi: 10.1038/s41467-017-02725-4

Fig. 3.

Fig. 3

PNp protective efficacy in mice. Mean body weight changes and survivals upon lethal dose challenges. Error bars represent mean ± SD and statistical analysis was performed with a log-rank test (***p < 0.001, n = 5). For viral challenges, mice were slightly anesthetized by inhalation of isoflurane, and a dose of 6 mLD50 virus in 50 μl PBS was dropped into two nares. Mouse body weight changes and survivals were monitored for 2 weeks. a PR8; b Aic; c p09; d reassortant Vtn (rVn); e Phi; and f reassortant SH (rSH)