Fig. 4.

Predominance of flux reversion in random metabolic networks. Fractions of reactions showing flux reversion (C_RV) (a), fractions of reactions showing flux reinforcement (C_RI) (b), C_RI/C_RV ratios (c), fraction of reactions showing PC > TC (d), f_p (e), and |log₁₀f_p| – |log₁₀f_a| (f) in the adaptations of random networks from the glucose environment to each of the 20 new environments examined. For each new environment, values estimated from different random networks are shown by a box plot, with symbols explained in the legend to Fig. 2d. The corresponding values for the E. coli iAF1260 network are shown by red diamonds