Figure 7.

PKC is involved in the SOC–ERK pathway. A, The effect of GF109203X (GF) on TG-induced ERK activation (n = 8 samples, F = 13.3, p values indicated in the graph. B, Representative TG-induced Ca²⁺ responses recorded in neurons pretreated with vehicle (Control) or GF. C, Summary of the effect of GF on TG-induced SOCE presented as the peak amplitude (n = 9–11 neurons, df = 19, t = 0.368, p = 0.717). D, The effect of GF on TG-induced modulation of A-type currents. E, Summary of the effects of GF on TG-induced modulation of A-type currents. For vehicle treatment, n = 5 neurons, df = 4, t = 5.868, p = 0.0042; for GF treatment, n = 6 neurons, df = 5, t = 0.941, p = 0.390. Values are means ± SEM, **p < 0.01, ***p < 0.001 compared with the control group by one-way ANOVA or the Student's t test; ^##p < 0.01 compared with the TG group.