Table 4.
Relationships between vascular risk factors and functional imaging parameters.
| Regional of interests | HDL and rCBF | hsCRP and PI | ||
|---|---|---|---|---|
| Simple correlation | Adjusted correlation# | Simple correlation | Adjusted correlation# | |
| Frontal | −0.03(0.817) | −0.25(0.313) | −0.34(0.002)* | −0.29(0.011) |
| Lateral temporal | −0.17(0.129) | −0.14(0.193) | −0.37(0.001)* | −0.29(0.006)* |
| Medial temporal | −0.08(0.481) | −0.54(0.625) | −0.30(0.007)* | −0.24(0.031) |
| Occipital | 0.19(0.101) | 0.16(0.122) | −0.15(0.199) | −0.08(0.470) |
| Parietal | 0.10(0.389) | 0.08(0.443) | −0.21(0.06) | −0.15(0.187) |
| Angular | 0.03(0.777) | 0.02(0.884) | −0.26(0.019) | −0.19(0.078) |
| Posterior Cingulate Cortex | 0.30(0.007)* | 0.28(0.006)* | −0.36(0.001)* | −0.28(0.007)* |
| Precuneus | 0.15(0.187) | 0.13(0.181) | −0.14(0.231) | −0.06(0.600) |
Abbreviations: HDL, high-density lipoprotein; hsCRP, high sensitive C-reactive protein; rCBF, relative cerebral blood flow; PI, perfusion index.
#Adjusted for age and clinical dementia rating sum of box.
*p < 0.01; numbers indicate correlation coefficient (p-value).