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. 2018 Jan 24;8:1490. doi: 10.1038/s41598-018-19969-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Longitudinal optical coherence tomography (OCT) scans of an eye following AAV2-DCX-GFP injection. (a) Representative OCT scans in one animal obtained from the raster scanning pattern at pre-injection and at weeks 1, 2, 3, 4 and 5 after intravitreal injection. Red lines in pre-injection scan show segmentation of the inner retina (from inner plexiform layer to inner limiting membrane). (b) Mean inner retinal thickness measurement for the injected eyes measured longitudinally. No statistically significant differences were found between any of the time points. Error bars represent 95% confidence interval; n = 10.