Figure 3.
Functional difference of seasonal Tep3 alleles as defined by the focal SNPs. Mean ± s.e. for bacterial load 24 h post-infection and survival 5 days post-infection for the Tep3 genotypes. (a) Higher survival for the spring genotype than the autumn or combination genotypes when infected with E. faecalis. (b) Additive effect of alleles when infected with P. rettgeri. (c) Lower constitutive Tep3 mRNA expression in the rare Tep3CG haplotype from the published dataset of DGRP flies [48]. (d,e) Frequency of Tep3 haplotypes in the Pennsylvania orchard across seasonal time. (f) Minimum spanning network illustrates that LD among the SNPs is maintained in distinct haplotypes. (Online version in colour.)