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Relationships among RH5 sequences analyzed by Forni et al. (19). (A) Phylogeny as depicted in reference 19. (B) Maximum-likelihood analysis of the same protein sequences, with branch lengths drawn to scale; the bar indicates 0.2 amino acid replacements per site. In each panel, the top sequence (red) is P. falciparum RH2b, a paralogue of RH5, and the bottom sequence (blue) is P. reichenowi strain CDC RH5; the other sequences (black) are RH5 from various P. falciparum strains.
