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VPS13C knock down increases free fatty acid release in BA. A) Free fatty acid release in media (n = 5), B) Glycerol release in media (n = 4) C) Free fatty acid/glycerol ratio (n = 4). D) Free fatty acid release in response to isoproterenol. From left to right: representative experiment, sensitivity (EC50) and maximal response to isoproterenol (n = 4). E) Free fatty acid release in response to 1 nM isoproterenol in the presence and absence of the ATGL inhibitor atglistatin (n = 4).
