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. 2017 Nov 11;7:45–56. doi: 10.1016/j.molmet.2017.11.004

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Time course of CL-316243 mediated dysfunction in Cpt2^A−/−BAT. A) H&E staining of BAT from Cpt2^A−/− and Cpt2^lox/lox mice after injection with 1 mg/kg CL-316243 for 0, 2, 4, 6, or 8 days. Scale bar, 200 um. B) Western blots of representative proteins in oxidative phosphorylation complexes I, II, III, and V in BAT from 12-week old Cpt2^A−/− and Cpt2^lox/lox mice injected with 1 mg/kg CL-316243 for 0, 2, 4, 6, 8, and 10 days. C) Mitochondrial protein expression in BAT from 12-week old Cpt2^A−/− and Cpt2^lox/lox mice injected with 1 mg/kg CL-316243 for 0, 2, 4, 6, 8, and 10 days.