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. 2017 Nov 6;7:1–11. doi: 10.1016/j.molmet.2017.10.012

Figure 6.

Figure 6

NAMPT overexpression in skeletal muscle and voluntary exercise training increased mitochondrial gene expression but not SIRT1 gene expression and complex III protein content. Gene expression of (A) SIRT1 and genes related to (B) mitochondrial biogenesis, (C) oxidative phosphorylation, (D) oxidative stress modulation, and (E) substrate selection in red quadriceps. (F) Complex III protein content in red quadriceps. WT sed = sedentary Wild Type; NamptTg sed = sedentary NamptTg; WT ex = exercised Wild Type; NamptTg ex = exercised NamptTg. Letters indicate significant differences between groups (p < 0.050). Data are normalized to WT sed, and are mean ± SEM.