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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Photochem Photobiol. 2017 May 9;93(4):1016–1024. doi: 10.1111/php.12758

Figure 2. Naproxen reduces proliferation and induces apoptosis in UVB-induced SCC and BCC of Ptch1+/−/SKH-1 hairless mice.

Figure 2

(a) H&E staining showing histology of SCC; (b) immunohistochemical analysis showing expression of PCNA (red); (c) immunofluorescence staining of cyclin D1 (red); (d) Western blot and densitometric analysis showing epidermal expression of PCNA and cyclin D1; (e) TUNEL-positive apoptotic cells (green); (f) Western blot analysis of apoptosis-related proteins, Bax and Bcl2. Scale bar 20μm. * p<0.05 was considered statistically significant.