Nearly half of all operators were low-volume operators (performed < 50 PCIs/year). Compared with intermediate- (50–100 PCIs/year) and high- (> 100 PCIs/year) volume operators, low-volume operators worked at lower volume hospitals, performed more emergency PCIs and primary PCIs for STEMI, less frequently used radial access, used more radiographic contrast dye, and more fluoroscopy minutes. Though in-hospital mortality was low (1.6% overall), it was higher for low- and intermediate-volume operators than for high-volume operators.