Table 2.
The top 34 probes associated with impaired fasting glucose.
| ILMNID | Hypo/Hyper | p-value | Chr | Pos | Gene | Gene region | Relation to island |
Enhancer |
|---|---|---|---|---|---|---|---|---|
| cg02333875 | ↑ | 7.19E-06 | 6 | 29618205 | S_Shore | TRUE | ||
| cg23606751 | ↓ | 1.67E-05 | 14 | 62228873 | SNAPC1 | TSS1500 | N_Shore | |
| cg07875069 | ↑ | 2.27E-05 | 7 | 129985025 | CPA5 | 1stExon | TRUE | |
| cg19412743 | ↓ | 2.95E-05 | 4 | 190747919 | TRUE | |||
| cg13916874 | ↑ | 3.14E-05 | 6 | 4286300 | S_Shelf | |||
| cg01403103 | ↓ | 3.33E-05 | 16 | 112852 | RHBDF1 | Body | Island | |
| cg17257444 | ↑ | 3.76E-05 | 11 | 59224044 | 0R4D6 | TSS1500 | ||
| cg22387253 | ↑ | 3.95E-05 | 15 | 61310104 | RORA | Body | TRUE | |
| cg21464903 | ↑ | 4.12E-05 | 8 | 41220059 | TRUE | |||
| cg14442421 | ↑ | 4.31E-05 | 9 | 19788257 | SLC24A2 | TSS1500 | Island | |
| cg21062902 | ↑ | 4.34E-05 | 6 | 34162022 | N Shelf | |||
| cg22212260 | ↑ | 4.62E-05 | 3 | 33468135 | UBP1 | Body | TRUE | |
| cg16218910 | ↑ | 4.76E-05 | 17 | 78878579 | RPTOR | Body | N_Shore | |
| cg10796022 | ↑ | 4.83E-05 | 8 | 61227705 | TRUE | |||
| cg23254538 | ↑ | 4.90E-05 | 6 | 31556919 | NCR3 | 3'UTR | ||
| cg10981651 | ↑ | 4.98E-05 | 5 | 153853545 | Island | TRUE | ||
| cg08031810 | ↑ | 5.10E-05 | 2 | 52856918 | Island | |||
| cg23200357 | ↑ | 5.16E-05 | 21 | 33108677 | S_Shelf | |||
| cg19872284 | ↑ | 5.23E-05 | 10 | 49607582 | TRUE | |||
| cg21944022 | ↑ | 5.28E-05 | 5 | 178288650 | ZNF354B | Body | S_Shore | |
| cg13491945 | ↑ | 5.37E-05 | 12 | 107078410 | RFX4 | TSS200 | ||
| cg11617821 | ↑ | 6.17E-05 | 4 | 75672135 | BTC | 3'UTR | ||
| cg06002516 | ↑ | 6.32E-05 | 12 | 57666521 | R3HDIv12 | Body | TRUE | |
| cg13853141 | ↓ | 6.65E-05 | 2 | 98329942 | ZAP70 | TSS200 | ||
| cg25375293 | ↓ | 6.87E-05 | 12 | 54718868 | COPZ1 | TSS200 | ||
| cg13993764 | ↑ | 6.88E-05 | 4 | 102269779 | PPP3CA | TSS1500 | S_Shore | |
| cg07904475 | ↓ | 7.04E-05 | 4 | 151500931 | LRBA | Body | Island | TRUE |
| cg21120478 | ↓ | 7.78E-05 | 12 | 6833063 | COPS7A | TSS200 | Island | |
| cg01382688 | ↓ | 7.91E-05 | 2 | 131672054 | N_Shore | |||
| cg00154957 | ↑ | 8.84E-05 | 1 | 109850562 | IvlYBPHL | TSS1500 | ||
| cg10196026 | ↑ | 9.01E-05 | 5 | 35003575 | AGA−2 | Body | ||
| cg13050884 | ↑ | 9.45E-05 | 3 | 171976122 | FNDC3B | Body | TRUE | |
| cg16997488 | ↓ | 9.70E-05 | 5 | 52083949 | ITGA1:PELO | 1stExon | Island | |
| cg00096979 | ↑ | 9.93E-05 | 16 | 2116141 | TSC2 | Body | S_Shore |
ILMNID: Illumina probe ID, ↑ Hypermethylated in cases, ↓ Hypomethylated in cases, Chr: Chromosome, Pos: Position build 37