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. 2018 Jan 25;18:16. doi: 10.1186/s12890-017-0571-7

Fig. 3.

Fig. 3

Respiratory-related medication use in the 12 months following the index datea. aOnly medications prescribed to >1% of patients in at least two cohorts are presented. bAll comparisons with ACO were statistically significant (p ≤ 0.001) except for the use of oral systemic corticosteroids (≤14 days) between the ACO and COPD cohorts (p = 0.500). ACO, asthma-COPD overlap; COPD, chronic obstructive pulmonary disease; CS, corticosteroid; ICS, inhaled corticosteroid; IgE, immunoglobulin E; LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist; LTRA, leukotriene receptor antagonist; NS, not significant; SABA, short-acting β2-agonist; SABD, short-acting bronchodilator; SAMA, short-acting muscarinic antagonist; Sys, systemic