Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 23;14:1744806917751322. doi: 10.1177/1744806917751322

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 5. — Cellular localization of CCR2-IR in T10 DRG at two weeks after STZ administration. Representative images of immunostaining with anti-CCR2 antibody in control (CT) (a) and diabetic (DM) (b) rats. Arrows represent CCR2-positive cells. Scale bar: 50 µm. Number of total and CCR2-IR neurons per section (c, e) and their size distribution (d, f) were determined in both the CT and DM groups. Data are shown as mean ± SEM, *p < 0.001 CT versus DM, n = 4 rats per group. CCR2 was exclusively expressed in small- and medium-sized DRG neurons in both the CT and DM rats (a, b, f). CCR2-IR neurons were significantly more numerous in the DM group than in the CT (a, b, e) despite no significant change between them in total DRG neurons per section (c). The number of CCR2-IR cells was relatively greater in small DRG neurons of DM rats according to the size distribution of the DRG neurons (d, f).