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. 2018 Jan 22;6:e4281. doi: 10.7717/peerj.4281

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©2018 Jamnongkan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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Xanthohumol in combination with praziquantel could serve as potential anti-inflammation, anti-oxidant and antifibrotic agents in liver fluke-induced inflammation in relation to CCA development. Legend: ↓, regulate; ⊥, inhibit.