Table 3.

Rare-variant association tests for genes associated with ciliopathies and subsets

Database	Gene list (No. of genes)	Bonferroni corrected P			Reference
		Burden	SKAT	SKAT-O
Invitae	Ciliopathies (102)	1.00000	1.00000	1.00000	[26]
	Joubert and Meckel-Gruber Syndromes (JBTMKS; 30)	0.39528	0.10536	0.19548	[26]
GHR	Joubert Syndrome (JBTS; 11)	0.09908	0.05076	0.08020	[27]
	Meckel Syndrome (MKS; 8)	1.00000	1.00000	1.00000	[28]

GHR Genetics home references, SKAT sequence kernel association test