Table 1.
Identification of differentially expressed proteins by BPA-dose dependent manner in mice
| Spot No.a) | Accession No.b) | Protein name (description)c) | Molecular functionc) |
|---|---|---|---|
| Up-regulated | |||
| 4702 | gi|148701559 | Anxa6 (annexin A6) | Calcium-dependent phospholipid binding, calcium ion bonding |
| 5205 | gi|27753960 | Abhd14b (abhydrolase domain containing 14b) | Cytoplasm hydrolase activity, metabolic process |
| 5604 | gi|3169729 | Hls2 (hematopoietic lineage switch 2) | Plasma glutamate carboxypeptidase |
| 8602 | gi|453155 | Krt9 (keratin 9) | Intermediate filament, perinuclear region of cytoplasm |
| 1808 | gi|121570 | Hspa5 (78 kDa glucose-regulated protein) | Protein binding, ER overload response, cellular response to IL-4 |
| 2803 | gi|119531 | Pdia4 (protein disulfide-isomerase A4) | Protein disulfide isomerase |
| 3802 | gi|6005942 | Vcp (valosin-containing protein) | Protein binding ubiquitin-dependent protein catabolic process |
| Down-regulated | |||
| 1501 | gi|104 | Atp5b (ATP synthase beta subunit) | Lipid metabolic process, MHC class 1 protein binding |
| 4202 | gi|10946936 | Ak1 (adenylate kinase 1) | ATP metabolic process, nucleoside diphosphate biosynthetic process |
ER, estrogen receptor; IL-4, interleukin 4.
a)
Location of the protein resolved by two-dimensional gel electrophoresis (Fig. 1) and identified by matrix assisted laser desorption ionization–time of flight mass spectrometry,
b)
Protein accession number from the NCBI nonredundant database,
c)
Annotation from the NCBI non-redundant database.