Table 4.

Kaplan-Meier estimated 5-year survival rate and mean cost for gastric cancer patients who underwent gastrectomy and neoadjuvant/adjuvant treatment from 2002 to 2013, overall and subgroup by demographic characteristics and the receipt of radiation therapy

	No.	Cost of primary treatment ($)a),b)	p-value	Net medical cost ($)b),c)	p-value	5-Year OS (%)	5-Year DSS (%)
Sex
Male	1,227	8,713±216	0.339	16,097±406	0.458	65.8	71.1
Female	592	8,351±309		15,572±574		68.2	71.3
Age (yr)
20-49	386	7,941±294	0.263	16,175±678	0.026	72.3	72.5
50-59	459	8,730±346		16,980±709		72.7	75.6
60-69	581	8,688±321		16,146±638		65.8	71.2
70-89	392	8,946±445		14,117±570		54.7	64.2
Surgery type
TG	517	11,513±398	< 0.001	20,868±699	< 0.001	48.5	52.1
STG	1,302	7,437±181		13,965±357		73.7	78.6
Charlson comorbidity index
0-1	1,139	7,575±187	< 0.001	14,787±385	< 0.001	67.5	69.9
2	327	8,892±346		16,632±715		69.3	72.7
3	144	11,193±890		18,792±1,426		67.6	80.3
≥ 4	209	12,416±812		19,418±1,350		55.1	71.9
Income
≤ 20 percentile	277	8,621±438	0.402	14,731±763	0.040	64.7	68.3
21-80 percentile	995	8,398±217		15,600±429		68.4	73.1
≥ 81 percentile	547	8,940±375		17,125±674		64.1	69.1
Health insurance type
NHI	1,761	8,591±181	0.893	16,029±339	0.089	67.1	71.8
Medical aid	58	8,727±766		12,814±1,421		48.5	48.5
Residential area
Metropolitan	859	8,687±283	0.622	16,089±479	0.643	66.9	71.7
Non-metropolitan	960	8,513±219		15,781±459		66.2	70.7
Hospital location
Metropolitan	1,594	8,575±194	0.697	15,770±344	0.207	66.9	71.5
Nonmetropolitan	225	8,742±382		17,045±1,120		63.9	68.4
Hospital volume (beds)
< 1,000	765	8,892±256	0.017	14,172±507	0.034	64.6	69.6
1,000-1,999	707	7,978±260		13,978±519		71.2	75.1
≥ 2,000	347	9,201±506		15,111±801		61.4	66.4
Disabled status
No	1,654	8,422±172	0.041	15,858±346	0.511	66.9	71.1
Yes	165	10,327±908		16,617±1,146		62.9	71.5
RT use
No	1,741	8,441±180	< 0.001	15,642±337	< 0.001	67.1	71.4
Yes	78	12,175±792		22,526±1,623		58.0	68.7
Death during study
Yes	607	11,234±422	< 0.001	24,160±701	< 0.001	-	-
No	1,212	7,274±147		11,804±288		-	-

OS, overall survival; DSS, disease-specific survival; TG, total gastrectomy; STG, subtotal gastrectomy; NHI, National Health Insurance; RT, radiotherapy.

^a)Defined as medical bill expenses claimed by medical service providers for primary treatment,

^b)All costs are presented in U.S. dollars, with an exchange rate of 1,103 Korean won to 1 U.S. dollar, which was the annual exchange rate in 2008,

^c)Defined as medical bill expenses claimed by medical service providers from diagnosis to death or last follow-up.