Table 6.
Severe exacerbations and healthcare resource utilizations stratified in COPD patients stratified by resource use status with 4 categories
| High resource usea | N of patients | Person years | N of events | Crude rates | Crude RR | Adjustedb RR |
|---|---|---|---|---|---|---|
| Severe exacerbations | ||||||
| No, No | 51,384 | 48,270 | 6764 | 0.14 | ref. | ref. |
| No, Yes Yes, No Yes, Yes |
32,269 1838 3057 |
30,516 1465 2521 |
8758 2341 5293 |
0.29 1.60 2.10 |
2.05 11.40 14.98 |
2.07 10.35 13.46 |
| Healthcare resource utilization | ||||||
| No, No | 51,384 | 48,270 | 179,149 | 3.71 | ref. | ref. |
| No, Yes Yes, No Yes, Yes |
32,269 1838 3057 |
30,516 1465 2521 |
119,372 12,002 18,976 |
3.91 8.19 7.53 |
1.05 2.21 2.03 |
1.12 1.89 1.95 |
Abbreviation: RR Relative ratio
aCategorical variable with 4 combinations of the following two variables: history of respiratory hospitalizations (≥2 within 1 year), and current medication use of ICS and LABA and/or LAMA (within 4 months). Categories (No/No, No/Yes, Yes/No, Yes/Yes)
bAdjusted for age, gender, time since diagnosis, and Charlson comorbidity index