Fig. 2.
Heterogeneity of cerebrospinal fluid (CSF) neurofilament light chain protein (NfL) and total tau (t-tau) levels in Creutzfeldt-Jakob disease (CJD) MM1, VV2, and MV2K. Among CJD subtypes, CSF NfL and t-tau levels reflect both the rate of clinical progression and the relative extent of subcortical (deep nuclei, brainstem, and cerebellum) and cortical pathology